Describing and analyzing a typical measles outbreak assignment

Individual Assignment

The purpose of this assignment is to get some experience describing and analyzing a typical measles outbreak. Here is the scenario: You are an epidemiologist with the state immunization program. Your Division Director wants information on a recent measles outbreak. In particular, this outbreak has been in the news and your Director wants an analysis so he can respond to questions (eg how come a third of the cases are in vaccinated persons does the vaccine work?). The template attached is a very typical example of how you might respond to this request. Fill in the rest of the template including:

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a graph representing the epidemiological curve of the outbreak,

a narrative description of the salient features of the outbreak and the epi curve,

an analysis of vaccine efficacy (including a calculation of vaccine efficacy for this outbreak), and

a list of conclusions and recommendations for your Director based on your description and analyses.

The results of the case and contact investigations are below:

Case investigation:

A pediatrician had evaluated a 10-year-old child in the emergency department on May 10th, 2016 who was suspected to have Kawasaki disease. The child had arrived from India on May 8th and had developed a rash on May 9th. A review of medical records led the investigators to reconsider the rash illness in the 10-year-old child as a possible measles case following the laboratory confirmation of measles by IgM testing.

A total of 108 contacts were identified as exposed to the index case or to the siblings. Of the 108, 100 were vaccinated and 7 were unvaccinated. A total of twelve measles cases were diagnosed in this outbreak. All cases are summarized in the table below.

Case Description Age Onset date Vaccination h/o Lab Confirmed y/n
Index 10 09-May no vaccine y
sibling 1 7 23-May no vaccine y
sibling 2 9 26-May no vaccine n
father 34 26-May 1 MMR (no record) y
contact – index 12 mo 27-May no vaccine y
pediatrician 51 28-May 3 MMRs y
contact – siblings 47 03-Jun 1 MMR (no record) y
contact – siblings 8 04-Jun no vaccine y
contact – siblings 7 05-Jun no vaccine y
contact – siblings 9 05-Jun no vaccine y
contact – siblings 10 06-Jun 2 MMRs y


Measles assignment

Measles assignment
Criteria Ratings Pts
Analysis and narrative – accuracy of graph, accuracy of calculations, accuracy of interpretation    
Conclusions and Recommendations (supported by the narrative and reflected key priorities in the outbreak)    
Writing – grammar, spelling, professionalism

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