Individual Assignment
The purpose of this assignment is to get some experience describing and analyzing a typical measles outbreak. Here is the scenario: You are an epidemiologist with the state immunization program. Your Division Director wants information on a recent measles outbreak. In particular, this outbreak has been in the news and your Director wants an analysis so he can respond to questions (eg how come a third of the cases are in vaccinated persons does the vaccine work?). The template attached is a very typical example of how you might respond to this request. Fill in the rest of the template including:
a graph representing the epidemiological curve of the outbreak,
a narrative description of the salient features of the outbreak and the epi curve,
an analysis of vaccine efficacy (including a calculation of vaccine efficacy for this outbreak), and
a list of conclusions and recommendations for your Director based on your description and analyses.
The results of the case and contact investigations are below:
Case investigation:
A pediatrician had evaluated a 10-year-old child in the emergency department on May 10th, 2016 who was suspected to have Kawasaki disease. The child had arrived from India on May 8th and had developed a rash on May 9th. A review of medical records led the investigators to reconsider the rash illness in the 10-year-old child as a possible measles case following the laboratory confirmation of measles by IgM testing.
A total of 108 contacts were identified as exposed to the index case or to the siblings. Of the 108, 100 were vaccinated and 7 were unvaccinated. A total of twelve measles cases were diagnosed in this outbreak. All cases are summarized in the table below.
| Case Description | Age | Onset date | Vaccination h/o | Lab Confirmed y/n |
| Index | 10 | 09-May | no vaccine | y |
| sibling 1 | 7 | 23-May | no vaccine | y |
| sibling 2 | 9 | 26-May | no vaccine | n |
| father | 34 | 26-May | 1 MMR (no record) | y |
| contact – index | 12 mo | 27-May | no vaccine | y |
| pediatrician | 51 | 28-May | 3 MMRs | y |
| contact – siblings | 47 | 03-Jun | 1 MMR (no record) | y |
| contact – siblings | 8 | 04-Jun | no vaccine | y |
| contact – siblings | 7 | 05-Jun | no vaccine | y |
| contact – siblings | 9 | 05-Jun | no vaccine | y |
| contact – siblings | 10 | 06-Jun | 2 MMRs | y |
Measles assignment
| Measles assignment | ||
| Criteria | Ratings | Pts |
| Analysis and narrative – accuracy of graph, accuracy of calculations, accuracy of interpretation | ||
| Conclusions and Recommendations (supported by the narrative and reflected key priorities in the outbreak) | ||
| Writing – grammar, spelling, professionalism |
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